Pharmaceuticals cause internal injury (4)
I believe the answer is:
harm
'injury' is the definition.
(I know that injury can be written as harm)
'pharmaceuticals cause internal' is the wordplay.
'internal' says the answer is hidden in the clue.
'HARM' is hidden in the letters of 'pharmaceuticals cause'.
(Other definitions for harm that I've seen before include "Hurt, maim" , "Wound" , "Injure, injury" , "Injure or damage" , "Damage, hurt" .)