Pick up Rome VIP for a change (7)
I believe the answer is:
improve
'pick up' is the definition.
(I've seen this before)
'rome vip for a change' is the wordplay.
'for a change' is an anagram indicator.
'rome'+'vip'='romevip'
'romevip' with letters rearranged gives 'IMPROVE'.
(Other definitions for improve that I've seen before include "Enhance" , "Ameliorate" , "Change for the better" , "Train" , "Make progress" .)