Picture of Wise Men in the North East following one (7)
I believe the answer is:
imagine
'picture' is the definition.
(thesaurus)
'wise men in the north east following one' is the wordplay.
'wise men' becomes 'magi' (I've seen this before).
'in the' indicates putting letters inside.
'north east' becomes 'ne'.
'following' means one lot of letters go next to another.
'one' becomes 'i' (Roman numeral).
'ne' after 'i' is 'ine'.
'magi' going into 'ine' is 'IMAGINE'.
'of' acts as a link.
(Other definitions for imagine that I've seen before include "1971 John Lennon song" , "Classic Lennon song" , "John Lennon hit" , "Number one" , "Picture, conceive" .)