Pine church in outskirts of Adelaide (4)
I believe the answer is:
ache
'pine' is the definition.
(synonyms)
'church in outskirts of adelaide' is the wordplay.
'church' becomes 'ch' (common abbreviation).
'in' means one lot of letters goes inside another.
'outskirts of' says to hollow out the word (remove centre letters) (only letters on the outskirts).
'adelaide' with its centre removed is 'ae'.
'ch' inserted inside 'ae' is 'ACHE'.
(Other definitions for ache that I've seen before include "Hurt; yearn" , "Dull continuous pain" , "Persistent dull pain" , "Take an aspirin for it" , "Feel sore" .)