Pity Kent or ‘replacement’ with this! (10)
I believe the answer is:
kryptonite
'this' is the definition.
I know nothing about this answer so I can't judge whether it can be defined by this definition.
'pity kent or replacement' is the wordplay.
'replacement' is an anagram indicator.
'pity'+'kent'+'or'='pitykentor'
'pitykentor' is an anagram of 'KRYPTONITE'.
'with' is the link.
Can you help me to learn more?
(Other definitions for kryptonite that I've seen before include "threat to Kent" , "Mineral avoided by Superman" .)