Place it in South-East (4)
I believe the answer is:
site
'place' is the definition.
(site is a kind of place)
'it in south-east' is the wordplay.
'in' means one lot of letters goes inside another.
'south east' becomes 'se'.
'it' going within 'se' is 'SITE'.
(Other definitions for site that I've seen before include "Locate, position" , "Whereabouts" , "Situation (of a building)" , "Location; locate" , "Area set aside for building" .)