Place of learning is effeminate to you and me (6)
I believe the answer is:
campus
'place of learning' is the definition.
'campus' can be an answer for 'place' (thesaurus). I am not sure about the 'of learning' bit.
'effeminate to you and me' is the wordplay.
'effeminate' becomes 'camp' (I've seen this before).
'to you and me' becomes 'us'.
'camp'+'us'='CAMPUS'
'is' acts as a link.
Can you help me to learn more?
(Other definitions for campus that I've seen before include "university position" , "University buildings and grounds" , "Grounds for a student" , "University estate" , "University premises" .)