Played out, even across river (5)
I believe the answer is:
tired
'played out' is the definition.
('tired' can be similar in meaning to 'played out')
'even across river' is the wordplay.
'even' becomes 'tied' ('tied' can be a synonym of 'even').
'across' is an insertion indicator.
'river' becomes 'r'.
'tied' placed around 'r' is 'TIRED'.
(Other definitions for tired that I've seen before include "Ready to drop" , "Drowsy" , "Physically or mentally weary" , "Whacked" , "Sleepy" .)