Pleasing sound from Greek characters in charge (5)
I believe the answer is:
music
'pleasing sound' is the definition.
(I've seen this before)
'greek characters in charge' is the wordplay.
'greek characters' becomes 'mus' (more than one mu - mu is a Greek letter).
'in charge' becomes 'ic' (abbreviation for 'in charge').
'mus'+'ic'='MUSIC'
'from' acts as a link.
(Other definitions for music that I've seen before include "being confined by bars?" , "Sweet sound." , "'My - - ' , radio quiz" , "(Pleasant) sequence of sounds" , "A score represents it" .)