Pointless, maybe, when heartily fazed after Question 1 (4)
I believe the answer is:
quiz
'pointless maybe' is the definition.
(Pointless is a quiz show)
'heartily fazed after question 1' is the wordplay.
'heartily' indicates the central letters.
'after' says to put letters next to each other.
'question' becomes 'qu'.
'1' becomes 'i' (roman numeral).
The middle of 'fazed' is 'z'.
'qu'+'i'='qui'
'z' put after 'qui' is 'QUIZ'.
'when' is the link.
(Other definitions for quiz that I've seen before include "Pump" , "Questionable entertainment?" , "Q-and-A entertainment" , "General knowledge contest" , "Entertainment of questions and answers" .)