Crossword Genius

Poisoned, filled with cynicism initially -- is one? (7)

Ross

I believe the answer is:

sceptic

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'one?' is the definition.
Although both the answer and definition are singular nouns, I don't understand how they can define each other.

'poisoned filled with cynicism initially' is the wordplay.
'poisoned' becomes 'septic' (I've seen this before).
'filled with' means one lot of letters goes inside another.
'initially' says to take the initial letters.
The initial letter of 'cynicism' is 'c'.
'septic' going around 'c' is 'SCEPTIC'.

'is' acts as a link.

Can you help me to learn more?

(Other definitions for sceptic that I've seen before include "One might doubt it" , "Agnostic" , "One who doubts accepted opinions" , "One is inclined to doubt accepted opinions" , "A doubting Thomas" .)

I've seen this clue in The Telegraph.
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