Poisoner nicer, as reformed (7)
I believe the answer is:
arsenic
'poisoner' is the definition.
Although both the answer and definition are singular nouns, I can't understand how they can define each other.
'nicer as reformed' is the wordplay.
'reformed' indicates anagramming the letters.
'nicer'+'as'='niceras'
'niceras' anagrammed gives 'ARSENIC'.
Can you help me to learn more?
(Other definitions for arsenic that I've seen before include "Element No 33" , "Powerful poison" , "-- and Old Lace (play)" , "killer" , "Ratsbane" .)