Poles lost inclination (5)
I believe the answer is:
slope
'inclination' is the definition.
(slope is a kind of inclination)
'poles lost' is the wordplay.
'lost' indicates an anagram.
'poles' with letters rearranged gives 'SLOPE'.
(Other definitions for slope that I've seen before include "Inclination" , "Tilt with poles" , "Be inclined" , "Gradient, incline" , "decamp" .)