Police turn up expert to handle new loss (13)
I believe the answer is:
disappearance
'loss' is the definition.
(thesaurus)
'police turn up expert' is the wordplay.
'police' becomes 'dis' (detective inspectors or DIs).
'turn up' becomes 'appear' (I've seen this before).
'expert' becomes 'ance' (I can't explain this - if you can you should give a lot more credence to this answer).
'dis'+'appear'+'ance'='DISAPPEARANCE'
'to handle new' is the link.
I am not very happy about this link. Some or all of it may be part of another bit of the clue.
Can you help me to learn more?
(Other definitions for disappearance that I've seen before include "Vanishing act" , "Exit (maybe into thin air)" , "Departure from view" , "getaway" , "fading" .)