Polish dermatologist's second-stage acne treatment (8)
I believe the answer is:
elegance
'polish' is the definition.
(thesaurus)
'dermatologist's second-stage acne treatment' is the wordplay.
'dermatologist's second' becomes 'e' (I am not sure about this - if you are sure you should believe this answer much more).
'stage' becomes 'leg' ('leg' can be a synonym of 'stage').
'treatment' is an anagram indicator.
'acne' anagrammed gives 'ance'.
'e'+'leg'+'ance'='ELEGANCE'
Can you help me to learn more?
(Other definitions for elegance that I've seen before include "Refinement, polish" , "Grace and stylishness" , "Fine quality" , "Fashionable grace" , "Sophistication" .)