Poor area to reach, going outside hotel (6)
I believe the answer is:
ghetto
'poor area' is the definition.
(I've seen this before)
'reach going outside hotel' is the wordplay.
'reach' becomes 'getto' (getting to is a kind of reaching).
'going outside' is an insertion indicator (the word goes on the outside of inserted letters).
'hotel' becomes 'h' (phonetic alphabet: alpha, bravo, charlie etc.).
'getto' going around 'h' is 'GHETTO'.
'to' is the link.
(Other definitions for ghetto that I've seen before include "A poor quarter of a city" , "Restricted quarter" , "Ethic quarter" , "Poor city area" , "Slum part of city occupied by minority group" .)