Poor misguided fool in the lead somewhere in Japan (7)
I believe the answer is:
sapporo
'in japan' is the definition.
('Sapporo' is part of 'japan')
'poor misguided fool in the lead somewhere' is the wordplay.
I cannot quite understand how this works, but
an anagram of 'poor' is 'poro' which is within the answer.
'fool' could be 'sap' (synonyms) and 'sap' is found within the answer.
No letters remain.
This may be the basis of clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for sapporo that I've seen before include "Japanese city" , "Japan site of nineteen seventy two Winter Olympics" , "City of northern Japan - apropos (anag)" .)