Poorly Alec OK facing doctor somewhere in northern Italy (4,4)
I believe the answer is:
lake como
'somewhere in northern italy' is the definition.
(lake in Lombardy, Italy)
'poorly alec ok facing doctor' is the wordplay.
'poorly' indicates anagramming the letters (I've seen this in other clues).
'facing' says to put letters next to each other.
'doctor' becomes 'mo' (medical officer).
'alec'+'ok'='alecok'
'alecok' is an anagram of 'lakeco'.
'lakeco'+'mo'='LAKE COMO'
(Other definitions for lake como that I've seen before include "Water in North Italy" , "Italian tourist destination" , "Lombardy holiday area, favoured by George Clooney and Madonna" .)