Pope upset the French men (6)
I believe the answer is:
people
'men' is the definition.
(thesaurus)
'pope upset the french' is the wordplay.
'upset' is an anagram indicator.
'the french' becomes 'le'.
'pope' is an anagram of 'peop'.
'peop'+'le'='PEOPLE'
(Other definitions for people that I've seen before include "Humans in general" , "Race - mankind" , "Persons in general" , "Humankind" , "Men, women and children" .)