Popular group of twelve hurt (6)
I believe the answer is:
injury
'hurt' is the definition.
(I know that hurt can be written as injury)
'popular group of twelve' is the wordplay.
'popular' becomes 'in' ('in' can mean trendy).
'group of twelve' becomes 'jury' (I can't justify this - if you can you should give a lot more credence to this answer).
'in'+'jury'='INJURY'
Can you help me to learn more?
(Other definitions for injury that I've seen before include "Bodily damage" , "Sprain, perhaps" , "Wound" , "wrongful action" , "One of Dumas's three musketeers" .)