Popular musical blew end off - it had to happen (10)
I believe the answer is:
inevitable
'it had to happen' is the definition.
The definition suggests a singular noun which matches the answer.
'popular musical blew end off' is the wordplay.
'popular' becomes 'in' ('in' can mean trendy).
'musical' becomes 'evita' (Andrew Lloyd Webber musical).
'end off' means to remove the last letter.
'blew' with its last letter removed is 'ble'.
'in'+'evita'+'ble'='INEVITABLE'
Can you help me to learn more?
(Other definitions for inevitable that I've seen before include "Unavoidable, fated" , "Certain to happen" , "Inescapable" .)