Portrait perhaps of the wife of Francesco del Giocondo (4,4)

I believe the answer is:

mona lisa

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'portrait' is the definition.
(I've seen this before)

I don't understand how the rest of the clue works.

(Other definitions for mona lisa that I've seen before include "Fertiliser from seabirds" , "Da Vinci painting" , "Picture" , "Leonardo da Vinci's enigmatic portrait" , "Famous painting of enigmatic woman by de Vinci" .)

I've seen this clue in The Times.

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