Positive ruse would work (4)
I believe the answer is:
sure
'positive' is the definition.
(similar in meaning)
'ruse would work' is the wordplay.
'ruse' can be anagrammed to 'SURE'.
Though, I am not sure how this is indicated.
Can you help me to learn more?
(Other definitions for sure that I've seen before include "Certain, confident" , "The old sewer" , "Feeling no doubt" , "See 12" , "Undoubtedly true" .)