Possibly resign as a musician (6)
I believe the answer is:
singer
'a musician' is the definition.
(I know that singer is a type of musician)
'possibly resign' is the wordplay.
'possibly' indicates anagramming the letters.
'resign' anagrammed gives 'SINGER'.
'as' acts as a link.
(Other definitions for singer that I've seen before include "One performing song" , "Diva perhaps" , "inventor who got everything sewn up?" , "Warbler" , "Vocalist" .)