Potty covered in hair, as an artefact (3-4)
I believe the answer is:
man-made
'as an artefact' is the definition.
I can't judge whether this definition defines the answer.
'potty covered in hair' is the wordplay.
'potty' becomes 'mad' (I can't explain this - if you can you should give a lot more credence to this answer).
'covered in' indicates putting letters inside.
'hair' becomes 'mane' (mane is a kind of hair).
'mad' placed inside 'mane' is 'MAN-MADE'.
Can you help me to learn more?
(Other definitions for man-made that I've seen before include "Constructed by humans, not by nature" , "Caused by humans" , "Artificial, synthetic" .)