Prepare miners for combat in depressed region (6)
I believe the answer is:
armpit
'combat in depressed region' is the definition.
The definition and answer can be both body parts as well as being singular nouns.
Perhaps you can see a link between them that I can't see?
'prepare miners' is the wordplay.
'prepare' becomes 'arm'.
'miners' becomes 'pit' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'arm'+'pit'='ARMPIT'
'for' is the link.
Can you help me to learn more?
(Other definitions for armpit that I've seen before include "Depression under an upper limb" , "part of the body" , "Bodily hollow" , "A sort of hollow" , "Where to put a crutch" .)