Priest breaking wind instrument in US city (9)
I believe the answer is:
kalamazoo
'us city' is the definition.
(I've seen this before)
'priest breaking wind instrument' is the wordplay.
'priest' becomes 'lama' (lama is a kind of priest).
'breaking' indicates putting letters inside.
'wind instrument' becomes 'kazoo' (kazoo is a kind of wind instrument).
'lama' going within 'kazoo' is 'KALAMAZOO'.
'in' acts as a link.
(Other definitions for kalamazoo that I've seen before include "US city" , "I've got a gal in - (Glenn Miller)" , "Michigan city" .)