Prince finally among the creme de la creme. Harry? (5)
I believe the answer is:
beset
'harry?' is the definition.
('beset' can be a synonym of 'harry')
'prince finally among the creme de la creme' is the wordplay.
'finally' says to take the final letters.
'among' indicates putting letters inside.
'the creme de la creme' becomes 'best'.
The final letter of 'prince' is 'e'.
'e' placed into 'best' is 'BESET'.
(Other definitions for beset that I've seen before include "Attacked from all sides" , "Press" , "Trouble or harass persistently" , "Encircled, attacked" , "Harry" .)