Prisoner's room has nothing in the way of an instrument (5)
I believe the answer is:
cello
'way of an instrument' is the definition.
'cello' can be an answer for 'instrument' (cello is a kind of instrument). I'm unsure of the 'way of an' bit.
'prisoner's room has nothing' is the wordplay.
'prisoner's room' becomes 'cell' (I've seen this in another clue).
'has' means one lot of letters go next to another.
'nothing' becomes 'O' (looks like zero - 0).
'cell'+'o'='CELLO'
'in the' is the link.
Can you help me to learn more?
(Other definitions for cello that I've seen before include "Lloyd Webber's instrument" , "Viola's bigger brother?" , "Tortelier's instrument" , "10 [INSTRUMENT]" , "Bass stringed instrument" .)