Problem children (5)
I believe the answer is:
issue
I believe this clue is a double definition.
'problem' is the first definition.
(issue can mean a problem or difficulty)
'children' is the second definition.
(issue can mean someone's offspring)
(Other definitions for issue that I've seen before include "Sprogs" , "Argument" , "Produce" , "Matter for discussion" , "One of a series published periodically" .)