Proclaim girl in acute trouble (10)
I believe the answer is:
annunciate
'proclaim' is the definition.
(I've seen this before)
'girl in acute trouble' is the wordplay.
'girl' becomes 'Ann' (woman's name).
'trouble' indicates an anagram.
'in'+'acute'='inacute'
'inacute' with letters rearranged gives 'unciate'.
'ann'+'unciate'='ANNUNCIATE'
(Other definitions for annunciate that I've seen before include "Proclaim" , "Announce (arch.)" .)