Profoundly bad (4)
I believe the answer is:
evil
'profoundly bad' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for evil that I've seen before include "Malign" , "Wicked - social problem" , "Profoundly wicked" , "Very wicked or bad" , "Live (anag.)" .)