Prohibition on most of domestic fowl (6)
I believe the answer is:
bantam
'fowl' is the definition.
(bantam is a kind of fowl)
'prohibition on most of domestic' is the wordplay.
'prohibition' becomes 'ban' (ban is a kind of prohibition).
'on' says to put letters next to each other.
'most of' means to remove the last letter.
'domestic' becomes 'tame' ('tame' can be similar in meaning to 'domestic').
'tame' with its final letter taken off is 'tam'.
'ban'+'tam'='BANTAM'
(Other definitions for bantam that I've seen before include "Domestic fowl; small fighter" , "Supplier of eggs" , "poultry" , "Small chicken and light boxer" , "Lightweight boxer and hen" .)