Prospect uplifting the four of us? (4)
I believe the answer is:
view
'prospect' is the definition.
(I know that prospect can be written as view)
'uplifting the four of us?' is the wordplay.
'uplifting' says the letters should be written in reverse.
'the four of us?' becomes 'weIV' (IV is four in roman numerals).
'weiv' back-to-front is 'VIEW'.
(Other definitions for view that I've seen before include "Outlook" , "Aspect - prospect" , "Consider" , "What can be seen from a specified point" , "Watch TV, e.g." .)