Prudence and Regina getting off freight train (6)
I believe the answer is:
thrift
'prudence' is the definition.
(thrift is a kind of prudence)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for thrift that I've seen before include "Maritime growth" , "Practise this to save money" , "Careful use of resources" , "Careful control of resources" , "Careful spending" .)