Publisher tried changing around introduction to opus (6)
I believe the answer is:
editor
'publisher' is the definition.
(I have seen 'Senior publisher ' mean 'editor' so perhaps 'publisher' could also mean 'editor')
'tried changing around introduction to opus' is the wordplay.
'changing' is an anagram indicator.
'around' indicates putting letters inside.
'introduction to' indicates taking the first letters.
The initial letter of 'opus' is 'o'.
'tried' anagrammed gives 'editr'.
'editr' going around 'o' is 'EDITOR'.
(Other definitions for editor that I've seen before include "Rag worker" , "One is in charge of publication" , "Script-preparer" , "Chief journalist" , "One who determines the final content of a text" .)