Pursuer making the run (6)
I believe the answer is:
hunter
'pursuer' is the definition.
(thesaurus)
'making the run' is the wordplay.
'making' is an anagram indicator.
'the'+'run'='therun'
'therun' anagrammed gives 'HUNTER'.
(Other definitions for hunter that I've seen before include "Watch with hinged cover" , "Pursuer of game" , "Type of fob watch" , "woodsman" , "See 10" .)