Put out the litter (5)
I believe the answer is:
issue
I believe this is a double definition.
'put out' is the first definition.
('issue' can be a synonym of 'put out')
'the litter' is the second definition.
(thesaurus)
(Other definitions for issue that I've seen before include "Regular publication" , "Susie (anag.)" , "Result, outcome; topic" , "Continent" , "Difficulty" .)