Put the kibosh on (3)
(Other definitions for end that I've seen before include "scrap" , "Extreme" , "Aim - point - finish" , "Complete" , "SECOND PART OF 10" .)
'put the kibosh on' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for nix that I've seen before include "Cancel" , "water sprite" , "Nothing (sl.)" , "0" , "Spiteful water spirit" .)