Puts up with work done with us staggering (10)
I believe the answer is:
stupendous
'staggering' is the definition.
(thesaurus)
'puts up with work done with us' is the wordplay.
'up' says the letters should be written backwards (in down clue: letters go upwards).
'with' means one lot of letters go next to another.
'work' indicates anagramming the letters.
'with' means one lot of letters go next to another.
'puts' back-to-front is 'stup'.
'done' is an anagram of 'endo'.
'stup'+'endo'+'us'='STUPENDOUS'
(Other definitions for stupendous that I've seen before include "Astounding" , "Astoundingly huge" , "Extremely impressive" , "Phenomenal" .)