Puzzle setting? Kudos to you (6)
I believe the answer is:
sudoku
'puzzle' is the definition.
(I've seen this before)
'setting? kudos to you' is the wordplay.
'setting?' is an anagram indicator.
'to you' becomes 'u' (I've seen this in other clues).
'kudos' with letters rearranged gives 'sudok'.
'sudok'+'u'='SUDOKU'
(Other definitions for sudoku that I've seen before include "9 x 9, 1-9 puzzle" , "Number placement puzzle with a 9 x 9 grid" , "Popular logic-based puzzle" , "Numeric puzzle" , "Number game" .)