Puzzles nan, for starters, with senseless ageism (7)
I believe the answer is:
enigmas
'puzzles' is the definition.
(an enigma is a puzzle or mystery)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for enigmas that I've seen before include "'Puzzles, riddles (7)'" , "They're mysterious or difficult to understand" , "Puzzles - mysteries" , "'Mysteries, riddles (7)'" , "Problems" .)