Quarrel - one with a student of space (7)
I believe the answer is:
spatial
'space' is the definition.
(thesaurus)
'quarrel one with a student' is the wordplay.
'quarrel' becomes 'spat' (spatting is a kind of quarrelling**).
'one' becomes 'i' (Roman numeral).
'with' says to put letters next to each other.
'student' becomes 'l'.
'spat'+'i'+'a'+'l'='SPATIAL'
'of' is the link.
(Other definitions for spatial that I've seen before include "describing area?" , "Relating to space" , "A spital (anag)" , "Of arrangements in three dimensions" , "Relating to area" .)