Quarrel with some familiar guests (5)
I believe the answer is:
argue
'quarrel' is the definition.
(I've seen this before)
'with some familiar guests' is the wordplay.
'with' indicates the answer is hidden within the clue.
'ARGUE' is hidden in the letters of 'some familiar guests'.
(Other definitions for argue that I've seen before include "Debate or disagree" , "Reason" , "Exchange heated views" , "Disagree heatedly" , "Have a difference of opinion" .)