Queen Elizabeth I turned in anger (3)
I believe the answer is:
ire
'anger' is the definition.
(I've seen this before)
'queen elizabeth i turned' is the wordplay.
'queen elizabeth' becomes 'er' (abbreviation for Elizabeth Regina).
'turned' says the letters should be written in reverse.
'er'+'i'='eri'
'eri' reversed gives 'IRE'.
'in' is the link.
(Other definitions for ire that I've seen before include "exasperation" , "Displeasure" , "Choler" , "Anger among admirers" , "'Anger, wrath (3)'" .)