Queen in rage when drunk (6)
I believe the answer is:
regina
'queen' is the definition.
(Latin for 'queen')
'in rage when drunk' is the wordplay.
'when drunk' indicates an anagram (a drunken or disorderly form of the letters).
'in'+'rage'='inrage'
'inrage' is an anagram of 'REGINA'.
(Other definitions for regina that I've seen before include "in Canada" , "Something inserted" , "Queen (Latin)" , "our head of state" , "Queen in legal issues" .)