Queen is appropriate in disregarding Times (4)
I believe the answer is:
anne
'queen' is the definition.
(I've seen this before)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for anne that I've seen before include "Female name" , "- - of Cleves" , "--- Elliot, later Wentworth (J. Austen)" , "British queen" , "Queen, daughter of James II" .)