Queen opens in American Coliseum with Achy Breaky Heart? (7)
I believe the answer is:
cardiac
'heart?' is the definition.
(I've seen this before)
'queen opens in american coliseum with achy breaky' is the wordplay.
I cannot really understand how this works, but
'queen' could be 'card' (queen is a kind of playing card) and 'card' is located in the answer.
'american' could be 'a' (common abbreviation - e.g. in organisation names) and 'a' is present in the answer.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for cardiac that I've seen before include "Relating to 8 down, part one" , "Physiologically, of the heart" , "of hearts" , "Sort of surgery" , "Appertaining to the heart" .)