Radical doctor caught drinking wine (7)
I believe the answer is:
drastic
'radical' is the definition.
(drastic can mean radical or extreme)
'doctor caught drinking wine' is the wordplay.
'doctor' becomes 'Dr' (abbreviation).
'caught' becomes 'c' (cricket abbreviation).
'drinking' is an insertion indicator (inserted letters are consumed or drunk).
'wine' becomes 'asti' (Italian wine).
'dr'+'c'='drc'
'drc' going around 'asti' is 'DRASTIC'.
(Other definitions for drastic that I've seen before include "Severe - powerful" , "Extreme - forceful" , "Unsparing" , "Severe, radical (measures)" , "Very severe or serious" .)