Raised in Cincinnati, is of an acid nature (6)
I believe the answer is:
tannic
'raised in cincinnati is of an acid nature' is the definition.
I can't judge whether this definition defines the answer.
'raised in cincinnati is of' is the wordplay.
'raised' says the letters should be written in reverse.
'in' indicates a hidden word.
'cinnat' is hidden within 'cincinnati of'.
'cinnat' back-to-front is 'TANNIC'.
Can you help me to learn more?
(Other definitions for tannic that I've seen before include "Acid in tea and wine" , "Can tin be an acid?" , "This acid is used for dyeing and leather-making" , "Relating to a substance in tea and wine" , "Kind of acid in tea or tree-barks" .)